Description
Dapagliflozin and Sitagliptin Tablets come with the brand name “NEXTDAPA-SG 10/100” and are utilised in the treatment of type-2 diabetes mellitus. Type-2 diabetes mellitus, or non-insulin-dependent diabetes or adult-onset diabetes, is a pathological condition where blood sugar levels are elevated because of insulin deficiency, insulin resistance, or both.
Dapagliflozin and Sitagliptin Tablets consist of Dapagliflozin (sodium-glucose cotransporter-2 inhibitors) and Sitagliptin (dipeptidyl peptidase-4 inhibitor). Dapagliflozin reduces blood glucose levels and enhances the output of glucose in the urine. Sitagliptin reduces the liver's production of glucose by increasing insulin levels and reducing glucagon levels (the hormone that increases blood glucose levels). Therefore, Dapagliflozin+sitagliptin regulates blood sugar levels.
Medical Benefits
- This medicine is a dual combination drug of Dapagliflozin and Linagliptin as active components.
- Dapagliflozin promotes the elimination of excess sugar from the body through urine.
- Linagliptin reduces the hormones that increase blood glucose levels and stimulates insulin release from the pancreas. Dapagliflozin+sitagliptin together controls blood sugar levels.
Directions for Use
- Dapagliflozin and Sitagliptin Tablets should be taken with or without food or as directed by a physician.
- Adhere to your physician's advice on the amount and timing of this drug, for your own safety. Swallow it whole with water.
- Avoid crushing, breaking or chewing the tablet.
Storage
- Do not keep it within reach of children to avoid any accidents.
- Store it where tablets are in sealed packets and away from light and heat on a shelf.
- The tablet must be closed after use to ensure the quality of supplements.
Precautions
- It could interact with anti-diabetic (insulin glargine), diuretics (furosemide), hormone (levothyroxine) and corticosteroids.
- Avoid drinking alcohol as it may increase the health risks.
- Report hypoglycaemia (low blood sugar levels), heart issues and liver/kidney disease to your doctor.
- If you are pregnant or intending to become pregnant, report to your doctor before using this medicine.
- It can cause dizziness at times, so drive only if you are attentive after consuming this medication.
- Dapagliflozin and Sitagliptin Tablets shouldn't be used in children younger than 12 years.
Side Effects
- Sore throat
- Constipation
- Dizziness
- Diarrhea
- Headache
- Runny nose
Frequently Asked Questions (FAQs)
What is the health condition for which this medicine is taken?
This tablet is used to control type 2 diabetes. It reduces high blood sugar levels.
Can this medicine cause weight loss?
Yes, Dapagliflozin can make you lose some weight because it eliminates excess sugar from the body through urine. But it should not be taken solely to reduce weight.
Is this medicine taken for type 1 diabetes?
No, this drug is not for type 1 diabetes or individuals with diabetic ketoacidosis.
Can it be given to patients with cardiovascular conditions?
Dapagliflozin can benefit individuals with heart failure or with a history of heart disease, but your physician will determine whether it is appropriate for you.
Is it appropriate for kidney patients?
Individuals with severe kidney issues might not be able to use this drug. Your physician will monitor your kidney function every time.
Can this drug lead to low blood sugar?
Alone, it typically does not lead to low blood sugar. However, when used with insulin or other diabetes drugs, the risk might be greater.
What if I get urinary tract infections frequently?
It may increase the risk of urine or genital infections, particularly in women. Report repeated infections to your doctor.
Is this medication safe in older adults?
It can be administered in older adults, although physicians might monitor them more carefully for side effects such as dehydration or low blood pressure.